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KMID : 0857019990140010073
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Kosin Medical Journal
1999 Volume.14 No. 1 p.73 ~ p.80
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A Clinical Study on 43 Patients with Generalized Convulsive Status Epilepticus
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Kim Kwang-Soo
Lee Ju-Ho
Yoo Kyung-Moo
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Abstract
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Background : Status epilepticus (SE) is a major neurological and medical emergency requiring prompt treatment to prevent significant brain damage and possible mortality. Despite advances in current treatment technique, SE is still associated with a significant morbidity and mortality.
Methods Retrospective study from Kosin University Gospel Hospital has been utilized to investigate several clinical factors associated with SE. We studied the etiology, clinical features, and outcomes of 43 patients over the age of 10 years with generalized convulsive SE.
Results : The majority of patients (69.8%) had no history of previous seizures. CNS infection and alcohol withdrawal were the most prominent causes of SE. The other principle etiologies were idiopathic, head trauma, congenital anomaly, CVA, metabolic disorder, and brain tumor. Among 43 patients, twenty-two patients (51.2%) showed primary generalized tonic-clonic SE and the remainder had secondarily generalized partial SE. Frontal lobe was the most common anatomical site of lesion proven by brain CT or MRI. Thirty-nine patinets (90.7%) recovered without neurological sequelae, and 4 patients (9.3%) died.
Conclusion : Generalized convulsive SE associated with CNS infection was the most common, and caused a grave outcome.
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KEYWORD
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Status epilepticus, Etiology, Outcome
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